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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCQ
All Species:
24.85
Human Site:
T298
Identified Species:
36.44
UniProt:
Q04759
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04759
NP_006248.1
706
81865
T298
A
L
A
M
I
E
S
T
Q
Q
A
R
C
L
R
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
T298
A
L
A
M
I
E
S
T
Q
Q
A
R
C
L
R
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
C744
R
E
K
V
A
N
L
C
G
I
N
Q
K
L
L
Dog
Lupus familis
XP_849292
706
81555
T298
A
L
A
M
I
E
S
T
Q
Q
A
R
C
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q02111
707
81555
T298
A
L
A
M
I
E
S
T
Q
Q
A
R
S
L
R
Rat
Rattus norvegicus
Q9WTQ0
707
81732
T298
A
L
A
M
I
E
S
T
Q
Q
A
R
T
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
T298
A
L
A
M
I
E
S
T
Q
Q
A
R
S
L
R
Chicken
Gallus gallus
NP_001006133
699
80179
A288
N
Q
K
L
L
A
E
A
L
T
Q
V
S
Q
K
Frog
Xenopus laevis
Q7LZQ8
671
76506
L263
L
S
F
G
I
S
E
L
L
K
A
G
V
D
G
Zebra Danio
Brachydanio rerio
Q7SY24
670
76288
E264
S
L
S
F
G
I
S
E
L
Q
K
Q
G
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
D258
R
S
C
A
L
S
V
D
S
L
A
T
S
T
T
Honey Bee
Apis mellifera
XP_394743
624
71014
F253
G
S
T
F
I
Y
D
F
H
V
A
V
I
N
P
Nematode Worm
Caenorhab. elegans
P34722
704
80280
I301
L
S
E
M
Y
H
E
I
K
R
G
T
H
A
T
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
Q254
P
D
R
P
V
A
V
Q
K
Y
S
I
D
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
I545
A
N
K
I
L
K
T
I
Q
D
T
K
R
N
Q
Red Bread Mold
Neurospora crassa
P87253
1142
127954
T643
S
I
A
S
P
E
A
T
E
A
A
K
L
M
Y
Conservation
Percent
Protein Identity:
100
99.7
33.6
96.7
N.A.
94.7
94
N.A.
86.1
63.3
33.9
34.1
N.A.
42.9
43.2
47.1
47.8
Protein Similarity:
100
99.7
45.1
98.3
N.A.
97.5
96.8
N.A.
92.9
77.1
48.2
49.2
N.A.
58.7
58.9
64.1
62
P-Site Identity:
100
100
6.6
100
N.A.
93.3
93.3
N.A.
93.3
0
13.3
20
N.A.
6.6
13.3
6.6
0
P-Site Similarity:
100
100
20
100
N.A.
93.3
93.3
N.A.
93.3
20
20
46.6
N.A.
13.3
13.3
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.2
26.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.3
40.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
44
0
44
7
7
13
7
7
0
7
63
0
0
7
0
% A
% Cys:
0
0
7
0
0
0
0
7
0
0
0
0
19
0
0
% C
% Asp:
0
7
0
0
0
0
7
7
0
7
0
0
7
13
7
% D
% Glu:
0
7
7
0
0
44
19
7
7
0
0
0
0
0
0
% E
% Phe:
0
0
7
13
0
0
0
7
0
0
0
0
0
0
7
% F
% Gly:
7
0
0
7
7
0
0
0
7
0
7
7
7
0
7
% G
% His:
0
0
0
0
0
7
0
0
7
0
0
0
7
0
0
% H
% Ile:
0
7
0
7
50
7
0
13
0
7
0
7
7
0
0
% I
% Lys:
0
0
19
0
0
7
0
0
13
7
7
13
7
0
7
% K
% Leu:
13
44
0
7
19
0
7
7
19
7
0
0
7
44
7
% L
% Met:
0
0
0
44
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
7
7
0
0
0
7
0
0
0
0
7
0
0
13
0
% N
% Pro:
7
0
0
7
7
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
7
0
0
0
0
0
7
44
44
7
13
0
7
7
% Q
% Arg:
13
0
7
0
0
0
0
0
0
7
0
38
7
0
38
% R
% Ser:
13
25
7
7
0
13
44
0
7
0
7
0
25
0
0
% S
% Thr:
0
0
7
0
0
0
7
44
0
7
7
13
7
7
13
% T
% Val:
0
0
0
7
7
0
13
0
0
7
0
13
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
7
0
0
0
7
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _